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Oxycodone 15 mg is a narcotic opioid drug that works by altering the way the brain and nervous system respond to pain. It acts on the opioid receptors in the central nervous system to change how the body perceives pain, ultimately providing relief. Buy Oxycodone 15 mg online. It works by binding to opioid receptors in the brain and spinal cord. It is indicated for the treatment of moderate to severe pain. There is also an extended release formulation indicated for chronic moderate to severe pain requiring continuous opioid analgesics for an extended period. Oxycodone 15mg acts directly on a number of tissues not related to its analgesic effect.